Affordable Access

Access to the full text

Self-assembled matrix fabricated by Fe-metal organic frameworks and carboxymethyl cellulose for the determination of small molecules by MALDI-TOF MS

Authors
  • Yang, Yingchen1
  • Xia, Yan1
  • 1 Nankai University, 94 Weijin Road, Tianjin, 300071, China , Tianjin (China)
Type
Published Article
Journal
Microchimica Acta
Publisher
Springer-Verlag
Publication Date
Jul 14, 2020
Volume
187
Issue
8
Identifiers
DOI: 10.1007/s00604-020-04397-2
Source
Springer Nature
Keywords
License
Yellow

Abstract

A nanoprobe of laser desorption/ionization-time of flight mass spectrometry (LDI-TOF MS) for the determination of small molecules was developed that is based on the composition of Fe-metal organic frameworks (Fe-MOFs) and carboxymethyl cellulose-Na (CMC-Na). This material is a good adsorbent for small molecules via hydrogen bonding and π-interactions; we detected three molecules, dopamine, glyphosate, and pyrene. The detection limits for these compounds are 0.01 mg L−1, 1.50 μg L−1, and 0.01 μg L−1, respectively; the recoveries are 85–117%, 81–127%, and 89–115%, respectively. The relative standard deviations (~ 15%) and coefficients of determination of the calibration plot (~ 0.97) are satisfactory. The applicability of the chip for practical samples is demonstrated by quantifying pyrene in domestic water and polluted lake water; the recoveries are about 90~117% and 85~125% (n = 5), respectively; the RSDs are 9.4% and 13.5%, respectively. Graphical abstract

Report this publication

Statistics

Seen <100 times