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Selective electrical stimulation with current-field modulation

Authors
  • Kárason, Halldór1
  • Pilkington, Óskar2
  • Helgason, Thordur1
  • 1 Health Technology Center (Landspitali University Hospital, Reykjavík University),, Iceland , (Iceland)
  • 2 Thordur Helgason: Health Technology Center (Landspitali University Hospital, Reykjavík University),, Iceland , (Iceland)
Type
Published Article
Journal
Current Directions in Biomedical Engineering
Publisher
De Gruyter
Publication Date
Oct 01, 2021
Volume
7
Issue
2
Pages
803–806
Identifiers
DOI: 10.1515/cdbme-2021-2205
Source
De Gruyter
Keywords
License
Green

Abstract

Selective electrical stimulation using a multielectrode array is a promising technique that can potentially bring electrical stimulation treatment modalities a step forward. A microcontroller-controlled electrical stimulator system delivering a single pulse was designed, suitable for current-field modulation. The goal is to make electrical stimulation with surface electrodes more specific. A graphical user interface (GUI) was developed to control stimulation parameters and current-field within a multi-electrode array wirelessly. The stimulator generates arbitrary biphasic waveforms with a 5-bit resolution and high temporal precision (<10 μs) and was demonstrated to stimulate posterior lumbar root fibers in transcutaneous spinal cord stimulation (tSCS) treatment selectively. Current-field modulation throughout a sixteen-electrode array was achieved. The system has the goal to improve control of stimulation conditions in electrophysiological studies and time-dependent and site-specific stimulation patterns for neuromodulation applications. A novel feature is the current-field modulation ability of the stimulator for surface electrode arrays.

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