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Secondary structural entropy in RNA switch (Riboswitch) identification.

Authors
  • Manzourolajdad, Amirhossein
  • Arnold, Jonathan
Type
Published Article
Journal
BMC Bioinformatics
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Jan 01, 2015
Volume
16
Pages
133–133
Identifiers
DOI: 10.1186/s12859-015-0523-2
PMID: 25928324
Source
Medline
License
Unknown

Abstract

Various tests show that there is in fact a relationship between higher structural entropy and the potential for the RNA sequence to have alternative structures, within the limitations of our methodology. This relationship, though modest, is consistent across various tests. Understanding the behavior of structural entropy as a fairly new feature for RNA conformational dynamics, however, may require extensive exploratory investigation both across RNA sequences and folding models.

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