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Secondary acute myeloid leukemia in children with acute lymphoblastic leukemia treated with etoposide.

Authors
Type
Published Article
Journal
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Publication Date
Volume
11
Issue
2
Pages
209–217
Identifiers
PMID: 8426196
Source
Medline
License
Unknown

Abstract

This experience provides strong evidence for a link between epipodophyllotoxin therapy and secondary AML since none of these children received alkylating agent therapy or irradiation. This serious complication raises concern as to the appropriate use of epipodophyllotoxins in the treatment of childhood ALL.

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