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Search for relevant indications for selenium supplementation in thyroid diseases.

Authors
  • Wojciechowska-Durczynska, Katarzyna1
  • Lewinski, Andrzej2
  • 1 Department of Endocrinology and Metabolic Diseases, Medical University of Lodz, Poland. , (Poland)
  • 2 Polish Mother's Memorial Hospital Research Institute, Lodz, Poland. , (Poland)
Type
Published Article
Journal
Neuro endocrinology letters
Publication Date
Aug 05, 2017
Volume
38
Issue
4
Pages
237–241
Identifiers
PMID: 28871707
Source
Medline
License
Unknown

Abstract

Selenium plays a significant role in the thyroid function and its deficiency is considered by some authors to be a cause of thyroid disorders. The potential therapeutic influence of selenium supplementation in thyroid disease was investigated in several studies and some results were encouraging, however results were inconsistent and did not allow conclusion to be drawn. For that reason, we have performed a review study on relevance of selenium supplementation in thyroid disease. Till now, there is no strong evidence that selenium supplementation leads to clinical improvement in the course of autoimmune thyroiditis, nodular goitre or thyroid cancer. On the other hand, there is some evidence that selenium is effective in the treatment of orbitopathy; thus, the European Group on Graves' Orbitopathy (EUGOGO) recommends selenium administration in mild active orbitopathy.

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