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Search for a gene expression signature of breast cancer local recurrence in young women.

Authors
Type
Published Article
Journal
Clinical cancer research : an official journal of the American Association for Cancer Research
Publication Date
Volume
18
Issue
6
Pages
1704–1715
Identifiers
DOI: 10.1158/1078-0432.CCR-11-1954
PMID: 22271875
Source
Medline
License
Unknown

Abstract

Although the previously identified local recurrence signature was robust on another platform, we were neither able to validate it on an independent data set, nor able to define a strong gene expression classifier for local recurrence using a larger data set. We conclude that there are no significant differences in gene expression pattern in tumors from patients with and without local recurrence after breast-conserving treatment.

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