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Scrub typhus with multi-organ dysfunction syndrome and immune thrombocytopenia: a case report and review of the literature

Authors
  • Li, Weijia1
  • Huang, Lei1
  • Zhang, Weixing1
  • 1 Peking University Shenzhen Hospital, Shenzhen, 518036, People’s Republic of China , Shenzhen (China)
Type
Published Article
Journal
Journal of Medical Case Reports
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Dec 07, 2019
Volume
13
Issue
1
Identifiers
DOI: 10.1186/s13256-019-2299-x
Source
Springer Nature
Keywords
License
Green

Abstract

BackgroundScrub typhus is an acute infectious zoonotic disease caused by Orientia tsutsugamushi. Multi-organ dysfunction secondary to scrub typhus is hard to diagnose and has a high mortality rate. Only one case of scrub typhus with multi-organ dysfunction syndrome and immune thrombocytopenia has been reported thus far. In this study, we report a second case of scrub typhus with multi-organ dysfunction syndrome and immune thrombocytopenia, and we summarize its diagnosis and treatment.Case presentationA 43-year-old Han Chinese woman, a sanitation worker, was admitted to our hospital after 7 days of a skin infection and 5 days of a sore throat with fever and dizziness. A physical examination revealed the presence of an eschar on the right side of her neck. She had a history of insect bites during her sanitation work. A diagnostic evaluation identified scrub typhus as the primary illness, which was associated with multi-organ dysfunction syndrome and immune thrombocytopenia. She recovered completely after 15 days of treatment and extensive symptomatic supportive care.ConclusionWe report a second case of tsutsugamushi disease with multi-organ dysfunction syndrome and immune thrombocytopenia, which resolved after treatment and extensive care.

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