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Scoring mitotic activity in longitudinal sections of mouse embryonic incisors: significant differences exist for labial and lingual inner dental epithelia.

Authors
  • Nso, M
  • Senger, B
  • Ruch, J V
Type
Published Article
Journal
Journal of craniofacial genetics and developmental biology
Publication Date
Jan 01, 1992
Volume
12
Issue
3
Pages
159–166
Identifiers
PMID: 1517395
Source
Medline
License
Unknown

Abstract

The incisors of rodents (e.g., mice and rats) have an enamel-free lingual surface. It is not known how position specific differential evolution of labial versus lingual inner dental epithelium (IDE) is regulated. The patterns of mitotic activity of lingual and labial preodontoblasts and IDE were determined on sagittal sections of embryonic mouse incisors. No statistical differences were observed for the preodontoblasts. On the other hand the lingual IDE withdraw from the cell cycle before the corresponding labial cells. The incapacity of lingual IDE to differentiate into functional ameloblasts might be a consequence of a failure of cell kinetic dependent acquisition of competence to respond to specific epigenetic control mechanisms.

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