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Scanning tunnelling microscopy of 16S ribosomal RNA in water.

Authors
Type
Published Article
Journal
Biochemical and biophysical research communications
Publication Date
Volume
178
Issue
3
Pages
1280–1287
Identifiers
PMID: 1872848
Source
Medline
License
Unknown

Abstract

The scanning tunnelling microscope has been used to image 16S ribosomal RNA molecules in water electrophoretically deposited on graphite surface. Two kinds of images have been obtained: images showing aggregates of 16S ribosomal RNA molecules similar to those obtained from DNA solutions and others showing individual 16S ribosomal RNA molecules. An interesting characteristic of these images, recorded in constant current mode, is that the 16S ribosomal RNA molecules appear to be located below the graphite surface. The morphology and several structural parameters of the molecules were consistent with the data obtained from electron microscopy.

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