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SARS-CoV-2 Infection in Patients with Down Syndrome, Congenital Heart Disease, and Pulmonary Hypertension: Is Down Syndrome a Risk Factor?

Authors
  • Krishnan, Usha S1
  • Krishnan, Sankaran S2
  • Jain, Shipra3
  • Chavolla-Calderon, Mara B4
  • Lewis, Matthew5
  • Chung, Wendy K6
  • Rosenzweig, Erika B7
  • 1 Department of Pediatrics (Cardiology), Columbia University Irving Medical Center, New York, NY. Electronic address: [email protected]
  • 2 Department of Pediatrics (Pulmonology), New York Medical College, Valhalla, NY.
  • 3 Department of Pediatrics at Kings County Hospital Center, New York, NY.
  • 4 Department of Pediatrics at SUNY Downstate, New York, NY.
  • 5 Department of Cardiology (Adult Congenital Heart Disease) at Columbia University Irving Medical Center, New York, NY.
  • 6 Department of Pediatrics and Medicine, Columbia University Irving Medical Center, New York, NY.
  • 7 Department of Pediatrics (Cardiology), Columbia University Irving Medical Center, New York, NY.
Type
Published Article
Journal
The Journal of pediatrics
Publication Date
Oct 01, 2020
Volume
225
Pages
246–248
Identifiers
DOI: 10.1016/j.jpeds.2020.06.076
PMID: 32610168
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

With increasing information available about the epidemiology, pathophysiology, and management of patients affected with severe acute respiratory syndrome corona virus-2 infection, patients with Down syndrome, congenital heart disease, airway obstruction, and pulmonary hypertension present a unique challenge. This case series describes 3 patients with Down syndrome and respiratory failure secondary to coronavirus infection. Copyright © 2020 Elsevier Inc. All rights reserved.

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