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SARS-CoV-2: Combating Coronavirus Emergence

Authors
  • Graham, Rachel L.1
  • Baric, Ralph S.1, 2
  • 1 Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
  • 2 Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Type
Published Article
Journal
Immunity
Publication Date
May 08, 2020
Volume
52
Issue
5
Pages
734–736
Identifiers
DOI: 10.1016/j.immuni.2020.04.016
PMID: 32392464
PMCID: PMC7207110
Source
PubMed Central
License
Unknown

Abstract

The emergence and rapid global spread of SARS-CoV-2 mark the third such identification of a novel coronavirus capable of causing severe, potentially fatal disease in humans in the 21st century. As noted by Andersen et al. ( Nature Medicine ), the sequencing of proximal zoonotic ancestors to SARS-CoV-2 has aided in the identification of alleles that may contribute to the virus’ virulence in humans.

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