Affordable Access

Access to the full text

Sarcopenia as an independent predictor of the surgical outcomes of patients with inflammatory bowel disease: a meta-analysis

Authors
  • Erős, Adrienn1, 2
  • Soós, Alexandra1, 3
  • Hegyi, Péter1, 3, 4, 5
  • Szakács, Zsolt1, 2
  • Benke, Márton6
  • Szűcs, Ákos6
  • Hartmann, Petra7
  • Erőss, Bálint1, 2
  • Sarlós, Patricia1, 2, 5
  • 1 University of Pécs, 12 Szigeti Street, Pécs, 7624, Hungary , Pécs (Hungary)
  • 2 University of Pécs, 20 Ifjúság Street, Pécs, 7624, Hungary , Pécs (Hungary)
  • 3 University of Szeged, 6 Korányi fasor, Szeged, 6720, Hungary , Szeged (Hungary)
  • 4 University of Szeged Momentum Gastroenterology Multidisciplinary Research Group, 8-10 Korányi fasor, Szeged, 6720, Hungary , Szeged (Hungary)
  • 5 University of Pécs, 13 Ifjúság Street, Pécs, 7624, Hungary , Pécs (Hungary)
  • 6 Semmelweis University, 78 Üllői Street, Budapest, 1082, Hungary , Budapest (Hungary)
  • 7 University of Szeged, 1 Pulz Street, Szeged, 6724, Hungary , Szeged (Hungary)
Type
Published Article
Journal
Surgery Today
Publisher
Springer Singapore
Publication Date
Oct 15, 2019
Volume
50
Issue
10
Pages
1138–1150
Identifiers
DOI: 10.1007/s00595-019-01893-8
Source
Springer Nature
Keywords
License
Green

Abstract

Patients with inflammatory bowel disease (IBD) are at risk of sarcopenia, which is associated with poor clinical outcomes. We conducted this study to assess whether sarcopenia predicts the need for surgery and postoperative complications in patients with IBD. We performed a systematic search of four electronic databases, last updated in March, 2019. Data from studies comparing rates of surgery and postoperative complications in sarcopenic IBD patients versus non-sarcopenic IBD patients were pooled with the random-effects models. We calculated the odds ratios (OR) with a 95% confidence interval (CI). Ten studies with a collective total of 885 IBD patients were included in our meta-analysis. Although the analysis of raw data did not reveal significant differences between the two groups with respect to the rate of surgery and postoperative complications (OR = 1.826; 95% CI 0.913–3.654; p = 0.089 and OR = 3.265; 95% CI 0.575–18.557; p = 0.182, respectively), the analysis of adjusted data identified sarcopenia as an independent predictor for both of the undesirable outcomes (OR = 2.655; 95% CI 1.121–6.336; p = 0.027 and OR = 6.097; 95% CI 1.756–21.175; p = 0.004, respectively). Thus, early detection of sarcopenia in patients with IBD is important to prevent undesirable outcomes.

Report this publication

Statistics

Seen <100 times