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Sarcomatoid Variant of Bladder Carcinoma: A Case Report

Authors
  • Uemura, Koichi
  • Kawahara, Takashi
  • Ishida, Hiroaki
  • Nakaigawa, Noboru
  • Tanabe, Mikiko
  • Yao, Masahiro
  • Uemura, Hiroji
Type
Published Article
Journal
Case Reports in Oncology
Publisher
S. Karger AG
Publication Date
Sep 13, 2018
Volume
11
Issue
3
Pages
633–637
Identifiers
DOI: 10.1159/000492779
PMID: 30323753
PMCID: PMC6180258
Source
Karger
Keywords
License
Green
External links

Abstract

A 59-year-old man was referred to our hospital complaining of asymptomatic gross hematuria. Cystoscopy revealed a papillary tumor 8 cm in diameter filling the bladder. The patient underwent transurethral resection of the bladder tumor. The pathological findings revealed the sarcomatoid variant of urothelial carcinoma with a heterologous osteosarcomatous element. He had no metastasis according to our imaging analyses; thus, we planned radical cystectomy after two courses of neoadjuvant chemotherapy (gemcitabine and cisplatin). Following chemotherapy, enlarged pelvic lymph nodes were noted, and extremely aggressive local progression of the bladder tumor was confirmed. The patient ultimately died 6 months after his initial visit to our hospital.

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