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[Salmonella typhimurium--test system for detecting the mutagenic activity of environmental pollutants. II. Mutagenic effect of heavy metal salts in an in vitro system with metabolic activation].

Authors
  • Polukhina, G N
  • Kalinina, L M
  • Lukasheva, L I
Type
Published Article
Journal
Genetika
Publication Date
Jan 01, 1977
Volume
13
Issue
8
Pages
1492–1494
Identifiers
PMID: 334635
Source
Medline
License
Unknown

Abstract

Mutagenic effect of zinc chloride on Salmonella typhimurium strain was detected using in vitro metabolic activation system. Cadmium chloride showed no significant mutagenic activity in the same system. It is recommended to use both in vitro and in vivo metabolic activation systems in mutagenicity testing of chemicals.

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