Affordable Access

deepdyve-link
Publisher Website

Salivaomics for Oral Cancer Detection: An Insight

Authors
  • Chundru, V. Naga Sirisha1
  • Nirmal, Ramadas Madhavan2
  • Srikanth, B.3
  • Bojji, Manasa1
  • Midhun, Namburi4
  • Lakshmi, B. Jaya5
  • 1 Department of Oral and Maxillofacial Pathology, Malla Reddy Dental College for Women, Hyderabad, Telangana, India
  • 2 Department of Oral and Maxillofacial Pathology, Rajah Muthiah Dental College and Hospital, Chidambaram, Tamil Nadu, India
  • 3 , Telangana, India
  • 4 Department of Oral and Maxillofacial Pathology, CKS Theja institute of Dental Sciences, Tirupati, Andhra Pradesh, India
  • 5 Department of Oral Medicine and Radiology, Tirumala Institute of Dental Sciences and Research Centre, Nizamabad, Telangana, India
Type
Published Article
Journal
Journal of Pharmacy & Bioallied Sciences
Publisher
Wolters Kluwer - Medknow
Publication Date
Jun 05, 2021
Volume
13
Issue
Suppl 1
Identifiers
DOI: 10.4103/jpbs.JPBS_529_20
PMID: 34447042
PMCID: PMC8375914
Source
PubMed Central
Keywords
Disciplines
  • Review Article
License
Unknown

Abstract

Early detection is very crucial for successful management of oral cancer or any disease as such. Oral squamous cell carcinoma (OSCC) accounts for nearly 90% of malignancy of oral cavity. In the field of cancer research, there is always an ongoing quest for newer methods to lower the morbidity and mortality associated with OSCC. Saliva, a readily available noninvasive biofluid with constant contact with oral cancer lesion, offers an appealing alternative to serum and tissue testing. This review throws light on incorporation of newer technologies for harnessing the saliva to its fullest potential with increased specificity and sensitivity toward identification of cancer-specific molecular signatures for the development of point-of-care applications that could be used at the clinical setting.

Report this publication

Statistics

Seen <100 times