Salbutamol metered-dose inhaler with spacer for hyperkalemia: how fast? How safe?
- Published Article
- Publication Date
Mar 01, 1999
Salbutamol inhalation of 1,200 microg, using an MDI-S, has a relatively rapid onset of action that induces a consistent reduction in serum potassium levels, starting 3 to 5 min following delivery. Unexpectedly, a paradoxical elevation was detected in serum potassium levels in the first minutes following inhalation. This effect, although minor (0.15 mEq/L above baseline), may cast some doubt on the role of salbutamol inhalation as the first treatment for excessive hyperkalemia.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/10084465