Affordable Access

Access to the full text

Safety and efficacy of selective retina therapy (SRT) for the treatment of diabetic macular edema in Korean patients

Authors
  • Park, Young Gun1
  • Kim, Jae Ryun1
  • Kang, Seungbum1
  • Seifert, Eric2
  • Theisen-Kunde, Dirk2
  • Brinkmann, Ralf2
  • Roh, Young-Jung1, 3
  • 1 Catholic University of Korea, Department of Ophthalmology and Visual Science, Seoul, Republic of Korea , Seoul (South Korea)
  • 2 Medical Laser Center Lübeck GmbH, Lübeck, Germany , Lübeck (Germany)
  • 3 The Catholic University of Korea, Department of Ophthalmology, Yeouido St. Mary’s Hospital, College of Medicine, No. 62 Yeouido-dong, Yeongdeungpo-gu, Seoul, 150-713, Republic of Korea , Seoul (South Korea)
Type
Published Article
Journal
Graefe's Archive for Clinical and Experimental Ophthalmology
Publisher
Springer Berlin Heidelberg
Publication Date
Jan 23, 2016
Volume
254
Issue
9
Pages
1703–1713
Identifiers
DOI: 10.1007/s00417-015-3262-1
Source
Springer Nature
Keywords
License
Yellow

Abstract

PurposeSelective retina therapy (SRT) stimulates retinal pigment epithelium (RPE) cell migration and proliferation into irradiated areas. The objective of this study was to evaluate the efficacy and safety of SRT in Korean patients with clinically significant diabetic macular edema (DME).MethodsProspective non-randomized interventional case series study. Twenty-three eyes of 21 patients with clinically significant DME were treated with SRT and followed for 6 months. Patients underwent an evaluation of best corrected visual acuity (BCVA) in Early Treatment Diabetic Retinopathy Study (ETDRS) letters. Microperimetry was employed to measure macular sensitivity within the central 10° field, and the central macular thickness (CMT) and maximum macular thickness (MMT) were measured.ResultsAn improvement in BCVA of one to two ETDRS lines was observed in 41.2 % of patients and an improvement of greater than two lines in 29.4 %. Although there was no significant change in CMT (P > 0.05), MMT decreased from 465.8 ± 87.4 μm to 434.3 ± 83.9 μm (P = 0.006), and mean macular sensitivity increased from 20.8 ± 3.4dB to 22.5 ± 3.5dB (P = 0.02).ConclusionsThe gains in BCVA and improvement in macular sensitivity demonstrated that SRT may be used as an effective and safe treatment modality in Korean patients with clinically significant DME.

Report this publication

Statistics

Seen <100 times