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RPE and neuronal differentiation of allotransplantated porcine ciliary epithelium-derived cells.

Authors
  • Guduric-Fuchs, Jasenka
  • Chen, Wing
  • Price, Henrietta
  • Archer, Desmond B
  • Cogliati, Tiziana
Type
Published Article
Journal
Molecular vision
Publication Date
Jan 01, 2011
Volume
17
Pages
2580–2595
Identifiers
PMID: 22025893
Source
Medline
License
Unknown

Abstract

The efficient conversion to an RPE-like phenotype suggests that CE-derived cells could be a potential source of RPE for cell replacement. Our data also suggest that the ability of these cells to acquire neuronal phenotypes is influenced by the environment. Thus, pre-differentiated or (re)programmed CE-derived cells may be more amenable for retinal repair.

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