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RP5-833A20.1/miR-382-5p/NFIA-dependent signal transduction pathway contributes to the regulation of cholesterol homeostasis and inflammatory reaction.

Authors
  • Hu, Yan-Wei
  • Zhao, Jia-Yi
  • Li, Shu-Fen
  • Huang, Jin-Lan
  • Qiu, Yu-Rong
  • Ma, Xin
  • Wu, Shao-Guo
  • Chen, Zhi-Ping
  • Hu, Ya-Rong
  • Yang, Jun-Yao
  • Wang, Yan-Chao
  • Gao, Ji-Juan
  • Sha, Yan-Hua
  • Zheng, Lei
  • Wang, Qian
Type
Published Article
Journal
Arteriosclerosis Thrombosis and Vascular Biology
Publisher
Ovid Technologies Wolters Kluwer -American Heart Association
Publication Date
Jan 01, 2015
Volume
35
Issue
1
Pages
87–101
Identifiers
DOI: 10.1161/ATVBAHA.114.304296
PMID: 25265644
Source
Medline
Keywords
License
Unknown

Abstract

Our findings indicated that the RP5-833A20.1/miR-382-5p/NFIA pathway was essential to the regulation of cholesterol homeostasis and inflammatory reactions and suggested that NFIA may represent a therapeutic target to ameliorate cardiovascular disease.

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