The role of the oxidative state of glutathione and glutathione-related enzymes in anemia of hemodialysis patients.
- Published Article
- Publication Date
Dec 01, 1996
The findings suggest that: 1. Low GSH is related to decreased G-6-PD activities. 2. The reduction of peroxides with GPX are decreased by low GSH and low GPX activity. 3. GSSG may react with hemoglobin and causes protein aggregation in erythrocytes. These alterations cause hemolysis and could play a role in the pathogenesis of anemia in hemodialyzed patients.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/8939405