Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction

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Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction

Publisher
BioMed Central
Publication Date
Source
PMC
Keywords
Disciplines
  • Biology
License
Unknown

Abstract

Capacitation is an important physiological pre-requisite before the sperm cell can acrosome react and fertilize the oocyte. Recent reports from several laboratories have amply documented that the protein phosphorylation especially at tyrosine residues is one of the most important events that occur during capacitation. In this article, we have reviewed the data from our and other laboratories, and have constructed a heuristic model for the mechanisms and molecules involved in capacitation/acrosome reaction.

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