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The Role of the Ocular Tissue in SARS-CoV-2 Transmission

Authors
  • Peng, Michael1
  • Dai, Jiannong1
  • Sugali, Chenna Kesavulu1
  • Rayana, Naga Pradeep1
  • Mao, Weiming1, 2
  • 1 Eugene & Marilyn Glick Eye Institute, Indiana University School of Medicine, Indianapolis, IN
  • 2 Indiana University School of Medicine, Indianapolis, IN
Type
Published Article
Journal
Clinical Ophthalmology (Auckland, N.Z.)
Publisher
Dove
Publication Date
Oct 02, 2020
Volume
14
Pages
3017–3024
Identifiers
DOI: 10.2147/OPTH.S269868
PMID: 33061288
PMCID: PMC7537833
Source
PubMed Central
Keywords
License
Green

Abstract

The current global pandemic of coronavirus disease 2019 (COVID-19) has affected over 21 million people and caused over half a million deaths within a few months. COVID-19 has become one of the most severe public health crises in recent years. Compared to other pathogenic coronaviruses, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly infectious. Due to the lack of specific and effective treatment or vaccines, disease prevention and early detection are essential for establishing guidelines to mitigate further spread. The potential role of the ocular system in COVID-19 is still not clear but it has gained increasing attention. Here, we reviewed both clinical and research evidence on the ocular manifestations associated with COVID-19, the presence of SARS-CoV-2 in ocular surface tissues and tears, and the potential role of the eye in contracting SARS-CoV-2.

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