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[Role of Notch-Jagged/Delta signaling pathway in arthritis rats of reduced lung function induced by adjuvant].

Authors
  • Wan, Lei
  • Liu, Jian
  • Huang, Chuanbing
  • Wang, Yuan
  • Zhang, Xiaojun
  • Ruan, Liping
  • Wang, Yali
  • Ye, Wenfang
Type
Published Article
Journal
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
Publication Date
Feb 01, 2014
Volume
39
Issue
2
Pages
109–116
Identifiers
DOI: 10.11817/j.issn.1672-7347.2014.02.001
PMID: 24608384
Source
Medline
License
Unknown

Abstract

While arthritis occurs in AA rats, pulmonary function declines and significantly correlates with the expression of Notch receptor/ligand. The deposition of immune complex in the lung after the injection of CFA activates the Notch signaling pathway, and results in further decline of pulmonary function by signaling cascades.

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