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Role of miR-2392 in driving SARS-CoV-2 infection

Authors
  • McDonald, J. Tyson1, 2
  • Enguita, Francisco J.1, 3
  • Taylor, Deanne1, 4, 5
  • Griffin, Robert J.1, 6
  • Priebe, Waldemar1, 7
  • Emmett, Mark R.1, 8
  • Sajadi, Mohammad M.9
  • Harris, Anthony D.9
  • Clement, Jean9
  • Dybas, Joseph M.1, 4
  • Aykin-Burns, Nukhet5
  • Guarnieri, Joseph W.1, 4
  • Singh, Larry N.1, 4
  • Grabham, Peter1, 10
  • Baylin, Stephen B.1, 11
  • Yousey, Aliza1, 12
  • Pearson, Andrea N.12
  • Corry, Peter M.1, 6
  • Saravia-Butler, Amanda1, 13, 14
  • Aunins, Thomas R.15
  • And 31 more
  • 1 COVID-19 International Research Team
  • 2 Georgetown University School of Medicine, Washington, DC 20007, USA
  • 3 Instituto de Medicina Molecular João Lobo Antunes, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisbon, Portugal
  • 4 The Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA
  • 5 University of Pennsylvania, Philadelphia, PA 19104, USA
  • 6 University of Arkansas for Medical Sciences, Little Rock, AK 72211, USA
  • 7 University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
  • 8 University of Texas Medical Branch, Galveston, TX 77555, USA
  • 9 University of Maryland School of Medicine, Baltimore, MD 21201, USA
  • 10 Columbia University, New York, NY 10032, USA
  • 11 Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
  • 12 Morehouse School of Medicine, Atlanta, GA 30310, USA
  • 13 Logyx LLC, Mountain View, CA 94043, USA
  • 14 NASA Ames Research Center, Moffett Field, CA 94035, USA
  • 15 University of Colorado Boulder, Boulder, CO 80303, USA
  • 16 Sachi Bioworks Inc., Boulder, CO 80301, USA
  • 17 Antimicrobial Regeneration Consortium, Boulder Labs, Boulder, CO 80301, USA
  • 18 Quantum Biology Inc., Boulder, CO 80301, USA
  • 19 Weill Cornell Medicine, New York, NY 10065, USA
  • 20 KBR Space & Science, San Antonio, TX 78235, USA
  • 21 United States Air Force School of Aerospace Medicine, Lackland AFB, San Antonio, TX 78236, USA
  • 22 University of Chicago, Chicago, IL 60615, USA
  • 23 Iowa State University, Ames, IA 50011, USA
  • 24 University of Campinas, Sao Paulo, Brazil
  • 25 Fundação Getulio Vargas, Rio de Janeiro, Brazil
  • 26 National University of Asuncion, San Lorenzo, Central, Paraguay
  • 27 University of London, Egham Hill, Egham, UK
  • 28 University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Type
Published Article
Journal
Cell Reports
Publisher
Elsevier
Publication Date
Sep 30, 2021
Identifiers
DOI: 10.1016/j.celrep.2021.109839
PMCID: PMC8481092
Source
PubMed Central
Keywords
Disciplines
  • Article
License
Unknown

Abstract

McDonald et al. uncover a role of a circulating microRNA, miR-2392, as a potential biomarker for COVID-19 and begin development of a potential COVID-19 therapeutic and antiviral to inhibit miR-2392.

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