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The role of human achaete-scute homolog-1 in medullary thyroid cancer cells.

Authors
  • 1
Type
Published Article
Journal
Surgery
0039-6060
Publisher
Elsevier
Publication Date
Volume
134
Issue
6
Identifiers
PMID: 14668716
Source
Medline

Abstract

hASH1 down-regulation by raf-1 in MTC cells is associated with a significant decrease in hormone production. Thus, hASH1 appears to be important in the endocrine phenotype of MTC tumors and may serve as a molecular target for the treatment of patients with MTC.

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