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The Role of High Dose Interleukin-2 in the Era of Targeted Therapy.

Authors
  • Gills, Jessie
  • Parker, William P
  • Pate, Scott
  • Niu, Sida
  • Van Veldhuizen, Peter
  • Mirza, Moben
  • Holzbeierlein, Jeffery M
  • Lee, Eugene K
Type
Published Article
Journal
The Journal of urology
Publication Date
Sep 01, 2017
Volume
198
Issue
3
Pages
538–545
Identifiers
DOI: 10.1016/j.juro.2017.03.076
PMID: 28288839
Source
Medline
Keywords
License
Unknown

Abstract

Our data demonstrate that patient responses to high dose interleukin-2 and to targeted agents before and after receiving high dose interleukin-2 are independent. As such, carefully selected patients should be offered high dose interleukin-2 for the possibility of a complete and durable response without the fear of limiting the treatment benefit of targeted agents.

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