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Role of genomic and proteomic tools in the study of host-virus interactions and virus evolution.

Authors
  • Bhattacharjee, Soumen
Type
Published Article
Journal
Indian journal of virology : an official organ of Indian Virological Society
Publication Date
Dec 01, 2013
Volume
24
Issue
3
Pages
306–311
Identifiers
DOI: 10.1007/s13337-013-0150-3
PMID: 24426292
Source
Medline
Keywords
License
Unknown

Abstract

Viruses have short replication cycles and produce genomic variants within a host, a process that seems to adapt to their specific host and also enable them to infect new hosts. The recent emergence of viral genomic variants from the circulating pool within the host population and re-emergence of the old ones are posing serious threat to agriculture, animal husbandry and humanity as a whole. This review assesses the potential role of genomic and proteomic tools that can monitor not only the course of infection and pathogenesis, but also predict the pandemic or zoonotic epidemic potential of a virus in a previously exposed or immunologically naive biological population.

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