Affordable Access

Role of FMRFamide in the reproduction of Octopus vulgaris: molecular analysis and effect on visual input.

Authors
  • Di Cristo, Carlo
  • Delli Bovi, Pasquale
  • Di Cosmo, Anna
Type
Published Article
Journal
Peptides
Publisher
Elsevier
Publication Date
Oct 01, 2003
Volume
24
Issue
10
Pages
1525–1532
Identifiers
PMID: 14706531
Source
Medline
License
Unknown

Abstract

As a part of continuous research on the neurobiology of the cephalopods in general, and the neuroendocrine control of reproduction in Octopus vulgaris in particular, the presence, the molecular analysis and the effect of FMRFamide on the screening-pigment migration in the visual system have been analysed. FMRFamide immunoreactive fibres are present in the outer plexiform layer of the retina as well as in the plexiform zone of the deep retina. These fibres presumably come from optic and olfactory lobes. We isolated an incomplete Octopus FMRFamide cDNA which encodes an amino terminal truncated precursor containing several FMRFamide-related peptides (FaRPs) showing a high degree of identity with the FaRPs encoded in the precursor of Sepia officinalis, except for the presence of an Rpamide related peptide, present only in cnidarians. Finally, stimulation of isolated retina demonstrated that the effect of this tetrapeptide, coupled with dopamine, is the induction of an extreme adaptation of the retina to the light condition. This situation de facto inhibits sexual maturation. Our results on the effect of FMRFamide on the retina confirm the suggested hypothesis that this peptide plays an inhibitory role on the activity of optic gland.

Report this publication

Statistics

Seen <100 times