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[The role of dermorfin in regulating hibernation processes in mammals].

Authors
Type
Published Article
Journal
Fiziologicheskiĭ zhurnal SSSR imeni I. M. Sechenova
Publication Date
Volume
78
Issue
4
Pages
1–13
Identifiers
PMID: 1334852
Source
Medline
License
Unknown

Abstract

Administration of dermorphin (0.1 mg/kg, subcutaneously) induced a drop of body temperature, deceleration of initial vegetative parameters and development of hibernation-like state in susliks. The delayed effects involved a disorder in conditioning. The immunisation of hibernating susliks with the dermorphin conjugate leads to a gradual waking up of the animals, normalising of conditioning in all the parameters and occurrence of a motor component in avoidance conditioning. A possible specific role of the dermorphin in the mechanisms of hibernation, is discussed.

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