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Is there a role for chemoradiation in the management of cystadenocarcinoma of the pancreas?

Authors
  • Bradley, Edward L 3rd
  • Satchidanand, Sateesh K
Type
Published Article
Journal
Pancreas
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Jul 01, 2005
Volume
31
Issue
1
Pages
101–103
Identifiers
PMID: 15968257
Source
Medline
License
Unknown

Abstract

Despite a paucity of data, cystadenocarcinoma of the pancreas has been considered to be resistant to chemoradiation, with a limited effect similar to that of the more common pancreatic adenocarcinoma. We describe a case of a partially excised cystadenocarcinoma with a positive surgical margin that was treated by neoadjuvant chemoradiation. No epithelial elements were found on histologic examination after reresection. Three previous cases of dramatic response of pancreatic cystadenocarcinoma to chemoradiation have been described in the literature. The current dogma alleging poor response of pancreatic cystadenocarcinoma to chemoradiation may be in error.

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