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Role of carbohydrate response element-binding protein (ChREBP) in generating an aerobic metabolic phenotype and in breast cancer progression.

Authors
  • Airley, R E
  • McHugh, P
  • Evans, A R
  • Harris, B
  • Winchester, L
  • Buffa, F M
  • Al-Tameemi, W
  • Leek, R
  • Harris, A L
Type
Published Article
Journal
British Journal of Cancer
Publisher
Springer Nature
Publication Date
Feb 04, 2014
Volume
110
Issue
3
Pages
715–723
Identifiers
DOI: 10.1038/bjc.2013.765
PMID: 24366300
Source
Medline
License
Unknown

Abstract

The ChREBP expression may be reflective of an aerobic metabolic phenotype that may conflict with hypoxia-induced signalling but provide a mechanism for growth at the oxygenated edge of the tumours.

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