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The role of blood microfilters in clinical practice.

Authors
  • Kapadia, F1
  • Valentine, S
  • Smith, G
  • 1 Department of Anaesthetics, Queen Alexandra Hospital, Portsmouth, Hants, UK.
Type
Published Article
Journal
Intensive Care Medicine
Publisher
Springer Science and Business Media LLC
Publication Date
Jan 01, 1992
Volume
18
Issue
5
Pages
258–263
Identifiers
PMID: 1527254
Source
Medline
Language
English
License
Unknown

Abstract

Blood filters have been available since the 1930s. In this review we evaluate the role of microaggregate filters (MF) in certain transfusion complications, namely non-haemolytic febrile transfusion reactions (NHFTR), pulmonary injury, thrombocytopenia, fibronectin depletion and histamine release. We review the latest generation of leucocyte depleting filters and discuss their role in preventing alloimmunisation, immunosuppression and CMV transmission. Finally, we provide a rationale for the role of blood microfiltration in the present day practice of intensive care medicine.

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