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[The role of autonomic dysfunction in pathogenesis of irritable bowel syndrome].

Authors
  • Lebedeva, M A
  • Karganov, M Yu
  • Kozlova, Y A
  • Gotovtceva, G N
  • Tumurov, D A
  • Gudkova, A A
  • Guekht, A B
Type
Published Article
Journal
Patologicheskaia fiziologiia i èksperimental'naia terapiia
Publication Date
Jan 01, 2014
Issue
3
Pages
37–44
Identifiers
PMID: 25536789
Source
Medline
License
Unknown

Abstract

This article presents the results of a comparative study of autonomic disorders in patients with differernt types of irritable bowel syndrome (IBS). We used several clinical and instrumental methods, including the Veyn questionnaire, Kerdo autonomic index, skin sympathetic response and heart rate variability analysis. The results show a prevalence of sympathetic tone in all groups of patients (more pronounced in IBS with constipation), as well as an elevated stress index and decreased arterial baroreflex sensitivity. In the IBS with diarrhea group there was a reliable increase of power spectral density alvery low frequency and a lowered respiratory sinus arrhythmia.

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