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ROCK1 and ROCK2 regulate epithelial polarisation and geometric cell shape.

Authors
  • Kalaji, Ruba
  • Wheeler, Ann P
  • Erasmus, Jennifer C
  • Lee, Sang Y
  • Endres, Robert G
  • Cramer, Louise P
  • Braga, Vania M M
Type
Published Article
Journal
Biology of the Cell
Publisher
Wiley (Blackwell Publishing)
Publication Date
Aug 01, 2012
Volume
104
Issue
8
Pages
435–451
Identifiers
DOI: 10.1111/boc.201100093
PMID: 22462535
Source
Medline
License
Unknown

Abstract

We conclude that ROCK proteins are necessary for acquisition of elongated and geometric cell shape, two key events for epithelial differentiation.

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