Affordable Access

Robust polymer microfluidic device fabrication via contact liquid photolithographic polymerization (CLiPP).

Authors
  • Hutchison, J Brian
  • Haraldsson, K Tommy
  • Good, Brian T
  • Sebra, Robert P
  • Luo, Ning
  • Anseth, Kristi S
  • Bowman, Christopher N
Type
Published Article
Journal
Lab on a Chip
Publisher
The Royal Society of Chemistry
Publication Date
Dec 01, 2004
Volume
4
Issue
6
Pages
658–662
Identifiers
PMID: 15570381
Source
Medline
License
Unknown

Abstract

Microfluidic devices are commonly fabricated in silicon or glass using micromachining technology or elastomers using soft lithography methods; however, invariable bulk material properties, limited surface modification methods and difficulty in fabricating high aspect ratio devices prevent these materials from being utilized in numerous applications and/or lead to high fabrication costs. Contact Liquid Photolithographic Polymerization (CLiPP) was developed as an alternative microfabrication approach that uniquely exploits living radical photopolymerization chemistry to facilitate surface modification of device components, fabrication of high aspect ratio structures from many different materials with numerous covalently-adhered layers and facile construction of three-dimensional devices. This contribution describes CLiPP and demonstrates unique advantages of this new technology for microfabrication of polymeric microdevices. Specifically, the procedure for fabricating devices with CLiPP is presented, the living radical photopolymerization chemistry which enables this technology is described, and examples of devices made using CLiPP are shown.

Report this publication

Statistics

Seen <100 times