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Risks for multidrug-resistant pathogens in the ICU.

Authors
  • Martín-Loeches, Ignacio
  • Diaz, Emili
  • Vallés, Jordi
Type
Published Article
Journal
Current Opinion in Critical Care
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Oct 01, 2014
Volume
20
Issue
5
Pages
516–524
Identifiers
DOI: 10.1097/MCC.0000000000000124
PMID: 25188366
Source
Medline
License
Unknown

Abstract

Infections with MDROs can prolong hospital stay, promote antibiotic use and prolong duration of mechanical ventilation. Some points should be further explored in clinical research such as the heterogeneity of healthcare-associated pneumonia and the need of new drug development. Resistance to non fermentative Gram-negative bacilli, rising minimum inhibitory concentration in methicillin-resistant Staphylococcus aureus and spread of MDROs in patients without known risk factors suggest a review of guideline validation, taking into account ecology and severity of patient illness to provide timely and appropriate empiric therapy.

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