Affordable Access

Risks of congenital malformations and perinatal events among infants exposed to antidepressant medications during pregnancy.

Authors
Type
Published Article
Journal
Pharmacoepidemiology and drug safety
Publication Date
Volume
16
Issue
10
Pages
1086–1094
Identifiers
PMID: 17729378
Source
Medline
License
Unknown

Abstract

SSRIs and TCAs did not show a consistent link with congenital anomalies. Paroxetine exposure was not linked with an increased risk for cardiovascular anomalies, although our study power to detect a moderate increase in risk was limited. Infants exposed to antidepressants were at increased risk for preterm delivery. Both SSRIs and TCAs used during the third trimester appeared to increase the risk for perinatal complications and their use should be managed carefully among pregnant women with depression.

Statistics

Seen <100 times