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Risk of Serious Infection for Patients with Systemic Lupus Erythematosus Starting Glucocorticoids with or without Antimalarials.

Authors
  • Herrinton, Lisa J1
  • Liu, Liyan2
  • Goldfien, Robert2
  • Michaels, M Alex2
  • Tran, Trung N2
  • 1 From the Division of Research, Kaiser Permanente Northern California; Department of Rheumatology, The Permanente Medical Group, Oakland, California; Patient Safety Department, AstraZeneca/MedImmune; Observational Research Center, AstraZeneca, Gaithersburg, Maryland, USA.L.J. Herrinton, PhD, Division of Research, Kaiser Permanente Northern California; L. Liu, MD, Division of Research, Kaiser Permanente Northern California; R. Goldfien, MD, Department of Rheumatology, The Permanente Medical Group; M.A. Michaels, MD, Patient Safety Department, AstraZeneca/MedImmune; T.N. Tran, MD, PhD, Observational Research Center, AstraZeneca. [email protected]
  • 2 From the Division of Research, Kaiser Permanente Northern California; Department of Rheumatology, The Permanente Medical Group, Oakland, California; Patient Safety Department, AstraZeneca/MedImmune; Observational Research Center, AstraZeneca, Gaithersburg, Maryland, USA.L.J. Herrinton, PhD, Division of Research, Kaiser Permanente Northern California; L. Liu, MD, Division of Research, Kaiser Permanente Northern California; R. Goldfien, MD, Department of Rheumatology, The Permanente Medical Group; M.A. Michaels, MD, Patient Safety Department, AstraZeneca/MedImmune; T.N. Tran, MD, PhD, Observational Research Center, AstraZeneca.
Type
Published Article
Journal
The Journal of rheumatology
Publication Date
Aug 01, 2016
Volume
43
Issue
8
Pages
1503–1509
Identifiers
DOI: 10.3899/jrheum.150671
PMID: 27370880
Source
Medline
Keywords
License
Unknown

Abstract

Our findings suggest that the benefits of AM treatment for SLE may extend to preventing serious infections. Although the study included > 3000 patients, the statistical power to examine GC dosages < 15 mg/day was poor.

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