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Risk factors for amendment in type, duration and setting of prescribed outpatient parenteral antimicrobial therapy (OPAT) for adult patients with cellulitis: a retrospective cohort study and CART analysis.

Authors
  • Quirke, Michael1
  • Curran, Emma May2
  • O'Kelly, Patrick3
  • Moran, Ruth4
  • Daly, Eimear4
  • Aylward, Seamus4
  • McElvaney, Gerry2
  • Wakai, Abel1, 5
  • 1 Emergency Care Research Unit (ECRU),Royal College of Surgeons Ireland (RCSI), Dublin, Ireland. , (Ireland)
  • 2 Department of Medicine, RCSI, Beaumont Hospital, Dublin, Ireland. , (Ireland)
  • 3 Department of Statistics, Renal Medicine Unit,Beaumont Hospital, Dublin, Ireland. , (Ireland)
  • 4 VHI Homecare, Waverly Business Park, Dublin, Ireland. , (Ireland)
  • 5 Department of Emergency Medicine, Beaumont Hospital, Dublin, Ireland. , (Ireland)
Type
Published Article
Journal
Postgraduate Medical Journal
Publisher
BMJ
Publication Date
Sep 05, 2017
Identifiers
DOI: 10.1136/postgradmedj-2017-134968
PMID: 28874503
Source
Medline
Keywords
License
Unknown

Abstract

Increased age, NPSS and immunocompromise were associated with OPAT amendment. These identified risk factors can be used to support an evidence-based approach to patient selection for OPAT in cellulitis. The CART algorithm has good specificity but lacks sensitivity and is shown to be inferior in this study to logistic regression modelling.

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