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Risk of Amphetamine Use Disorder and Mortality Among Incident Users of Prescribed Stimulant Medications in the Veterans Administration.

Authors
  • Westover, Arthur N1, 2
  • Nakonezny, Paul A1, 2
  • Halm, Ethan A2, 3
  • Adinoff, Bryon1, 4
  • 1 Department of Psychiatry, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390, USA.
  • 2 Department of Clinical Sciences, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390, USA.
  • 3 Division of General Internal Medicine, Department of Internal Medicine, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390, USA.
  • 4 VA North Texas Health Care System, Dallas VAMC, 4500 South Lancaster Road, Dallas, TX, 75216, USA.
Type
Published Article
Journal
Addiction (Abingdon, England)
Publication Date
Dec 07, 2017
Identifiers
DOI: 10.1111/add.14122
PMID: 29215762
Source
Medline
License
Unknown

Abstract

In a US national cohort of adult incident stimulant medication users in the Veterans Affairs healthcare system, measured from fiscal years 2001 to 2012, comorbid substance use disorders were common and were risk factors for development of an amphetamine use disorder (AUD). Increased mortality risk among incident users of stimulant medications was observed among both those who later developed an AUD and those whose use was defined as off-label.

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