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The Rise of ST-Elevation Myocardial Infarction in Women of Northeast China

Authors
  • Wang, Yihe1
  • Newsome, Gary S.2
  • 1 Liaoning Health Industry Group, Shenyang, China
  • 2 Atlantic Analytical, Virginia Beach, VA, USA
Type
Published Article
Journal
Gerontology and Geriatric Medicine
Publisher
SAGE Publications
Publication Date
Feb 15, 2021
Volume
7
Identifiers
DOI: 10.1177/2333721421992250
PMID: 33644258
PMCID: PMC7894685
Source
PubMed Central
Keywords
License
Unknown

Abstract

The women of China’s Liaoning province display some morbidities in ways that defy medical explanation. Women have higher rates of hypertension, hypercholesterolemia, and metabolic syndrome than men, an anomaly for all three conditions. Most of these patients also suffer from Type 2 Diabetes Mellitus (T2DM) while there was a negative association between being female and T2DM for the rest of China. Each of these conditions can exist independently, but the increase in both their rates and congruence is a recent phenomenon. Stranger still is that Liaoning women are now presenting in hospital emergency departments with ST-Elevation Myocardial Infarction (STEMI), while diabetics predominantly suffer more benign Non-STEMI (NSTEMI) events. Confounding factors in any attempt to study this phenomenon include trace metals like manganese that have been shown to reduce systolic blood pressure in Asian men and raise it in Asian women. Some of the phenomenon may also be associated with the gene for Apolipoprotein 5, but its recent nature suggests other factors besides lipid profiles. Trace metals in the air, water, and diet of Liaoning province, or any urban environment, could play a role.

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