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Ring-closing metathesis: novel routes to aromatic heterocycles.

Authors
  • Donohoe, Timothy J1
  • Fishlock, Lisa P
  • Procopiou, Panayiotis A
  • 1 Chemistry Research Laboratory, University of Oxford, Oxford, OX1 3TA UK. [email protected]
Type
Published Article
Journal
Chemistry - A European Journal
Publisher
Wiley
Publication Date
Jan 01, 2008
Volume
14
Issue
19
Pages
5716–5726
Identifiers
DOI: 10.1002/chem.200800130
PMID: 18381742
Source
Medline
Language
English
License
Unknown

Abstract

Olefin metathesis has been established as an important and general reaction in synthetic organic chemistry. Recently, it has attracted interest as a powerful tool for the construction of aromatic heterocycles. The importance of heteroaromatic motifs in medicinal chemistry and biology, as well as the efficiency and wealth of metathesis transformations, have resulted in significant success in this rapidly developing area.

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