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Ribosomal resistance of clinical enterococcal to streptomycin isolates.

Authors
  • G M Eliopoulos
  • B F Farber
  • B E Murray
  • C Wennersten
  • R C Moellering
Publication Date
Mar 01, 1984
Source
PMC
Keywords
Disciplines
  • Biology
License
Unknown

Abstract

The mechanism of high-level resistance to streptomycin was studied in 12 clinical isolates of Streptococcus faecalis. Six strains produced streptomycin-modifying enzymes. Each of three enzyme-negative strains tested demonstrated ribosomal resistance to streptomycin. Lack of ribosomal susceptibility is a significant cause of high-level streptomycin resistance among clinical enterococcal isolates.

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