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Rheumatoid arthritis and bone health.

Authors
  • Ashai, Shanze1
  • Harvey, Nicholas C2
  • 1 MRC Lifecourse Epidemiology Unit, Southampton, UK.
  • 2 MRC Lifecourse Epidemiology Unit, Southampton, UK [email protected]
Type
Published Article
Journal
Clinical medicine (London, England)
Publication Date
Nov 01, 2020
Volume
20
Issue
6
Pages
565–567
Identifiers
DOI: 10.7861/clinmed.20.6.rabh
PMID: 33199321
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Rheumatoid arthritis (RA) is an inflammatory arthropathy affecting 1% of the population, with a female predominance. Systemic inflammation is a key component of RA disease; corticosteroids are often required to rapidly control disease activity. Both inflammation and corticosteroids, however, have an adverse effect on bone mineral density, potentially resulting in osteoporosis and an increased risk of fractures. In this article, we describe the link between RA and impaired bone health, together with appropriate strategies to maintain bone density and reduce fracture risk. Key approaches include achieving adequate control of inflammation, minimising corticosteroid use, monitoring bone mineral density and intervening with antiosteoporosis medications when indicated. © Royal College of Physicians 2020. All rights reserved.

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