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Rheumatic heart disease: current status of diagnosis and therapy.

Authors
  • Peters, Ferande1
  • Karthikeyan, Ganesan2
  • Abrams, Jessica3
  • Muhwava, Lorrein3
  • Zühlke, Liesl3, 4
  • 1 Cardiovascular pathophysiology and Genomic Unit, University of the Witwatersrand, Johannesburg, South Africa. , (South Africa)
  • 2 Cardiothoracic Sciences Centre, All India Institute of Medical Sciences, New Delhi, India. , (India)
  • 3 Division of Paediatric Cardiology, Department of Paediatrics, Red Cross Children's Hospital, University of Cape Town, Cape Town, South Africa. , (South Africa)
  • 4 Division of Cardiology, Department of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa. , (South Africa)
Type
Published Article
Journal
Cardiovascular diagnosis and therapy
Publication Date
Apr 01, 2020
Volume
10
Issue
2
Pages
305–315
Identifiers
DOI: 10.21037/cdt.2019.10.07
PMID: 32420113
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Rheumatic heart disease (RHD) is the only preventable cardiovascular disease which causes significant morbidity and mortality particularly in low- and middle-income countries. Early clinical diagnosis is key, the updated Jones criteria increases the likelihood of diagnosis in endemic settings, including the echo diagnosis of sub-clinical carditis, polyarthralgia and monoarthritis as well as amended thresholds of minor criteria. The mainstay of rheumatic heart valve disease (RHVD) is a thorough clinical and echocardiographic investigation while severe disease is managed with medical, interventional and surgical treatment. In this report we detail some of the more recent epidemiological findings and focus on the diagnostic and interventional elements of the specific valve lesions. Finally, we discuss some of the recent efforts to improve medical and surgical management for this disease. As we are already more than a year from the historic 2018 World Heart Organization Resolution against Rheumatic Fever and Rheumatic Heart Disease, we advocate strongly for renewed efforts to prioritize this disease across the endemic regions of the world. 2020 Cardiovascular Diagnosis and Therapy. All rights reserved.

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