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Review of the series "Disease of the year 2011: toxoplasmosis" pathophysiology of toxoplasmosis.

Authors
  • Subauste, Carlos S1
  • Ajzenberg, Daniel
  • Kijlstra, Aize
  • 1 Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA. [email protected]
Type
Published Article
Journal
Ocular Immunology and Inflammation
Publisher
Informa UK (Taylor & Francis)
Publication Date
Oct 01, 2011
Volume
19
Issue
5
Pages
297–306
Identifiers
DOI: 10.3109/09273948.2010.605198
PMID: 21970661
Source
Medline
License
Unknown

Abstract

Toxoplasma gondii is a major cause of chronic parasitic infection in the world. This protozoan can cause retino-choroiditis in newborns and in adults, both immunocompetent and immunodeficient. This disease tends to be recurrent and can lead to severe visual impairment. The authors review current knowledge on the role of parasite genetics in influencing susceptibility to ocular toxoplasmosis and on the immuno-pathogenesis of this disease.

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