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Reversible nutritional myopathy with myotonia in the protein-deficient rat given methionine.

Authors
  • Cummins, A G
  • Duncombe, V M
  • Bolin, T D
  • Davis, A E
Type
Published Article
Journal
The Australian journal of experimental biology and medical science
Publication Date
Apr 01, 1985
Volume
63 ( Pt 2)
Pages
127–137
Identifiers
PMID: 4038203
Source
Medline
License
Unknown

Abstract

Rats fed a protein-deficient synthetic diet developed hind limb weakness caused by a myopathy with myotonic features on electromyography. Deficiency of vitamin E and selenium, known causes of nutritional myopathy, were excluded. Methionine supplementation of the diet reversed the clinical signs of weakness within 12 h.

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