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[Reversibility of alterations induced by sexual steroids in various serum protein fractions, following application of hormonal contraceptives (author's transl)].

Authors
Type
Published Article
Journal
Zentralblatt für Gynäkologie
Publication Date
Volume
102
Issue
24
Pages
1421–1430
Identifiers
PMID: 6164184
Source
Medline
License
Unknown

Abstract

Reversibility of changes induced by sexual steroids was studied in 19 different serum protein fractions of 20 women. The following preparations were available for testing: Gravistat (ethinyl-oestradiol/norgestrel), Non-Ovlon (ethinyloestradiol/norethisterone-acetate), Ovosiston (mestranol/chlormadinone-acetate), and Deposiston (ethinyloestradiol-sulphonate/norethisterone-acetate). The tests were made towards the end of the 24th cycle on the pill and in the first cycle thereafter.--The proteins tested were found to be affected in a differentiated way and, throughout, depending on oestrogen levels. Reversal was rapid, but the phase of restitution usually was longer than the period of testing and follow-up. The long-lasting action of Deposiston was visualised also in its "reversal effect".

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