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Reversal of hepatotoxin-induced pre-fibrogenic events by Emblica officinalis--a histological study.

Authors
  • Mir, A I
  • Kumar, B
  • Tasduq, S A
  • Gupta, D K
  • Bhardwaj, S
  • Johri, R K
Type
Published Article
Journal
Indian journal of experimental biology
Publication Date
Jul 01, 2007
Volume
45
Issue
7
Pages
626–629
Identifiers
PMID: 17821859
Source
Medline
License
Unknown

Abstract

Efficacy of a herbal product of E. officinalis (fruit) (EO) has been evaluated against carbon tetrachloride (CCl4) and thioacetamide (TAA) induced changes in rat liver. Chronic treatment of CCl4 and TAA revealed abnormal histopathology indicative of pre-fibrogenic events. EO reversed such alterations with significant regenerative changes suggestive of its preventive role in prefibrogenesis of liver.

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