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Reversal of fibrosis: no longer a pipe dream?

Authors
Type
Published Article
Journal
Clinics in Liver Disease
1089-3261
Publisher
Elsevier
Publication Date
Volume
10
Issue
3
Identifiers
PMID: 17162224
Source
Medline
License
Unknown

Abstract

The reversal of liver fibrosis is not a new phenomenon. Treatment of the primary disease remains the most effective strategy, but new approaches to promote resolution of fibrosis are being built on the foundations that were provided by research into the basic mechanisms of fibrogenesis. A return to normal hepatic architecture from advanced fibrosis is achievable in some cases, and cirrhosis itself may be partly remediable.

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